Nanotechnology in drug delivery systems

نویسندگان

  • Fatemeh Mirjalili
  • Madjid Soltani
  • Pu Chen
چکیده

Nanotechnology is the engineering of purposeful systems at the molecular scale. It has an impact on every industry counting semiconductors, manufacturing, and biotechnology. Biomedical nanotechnology, bionanotechnology and nanomedicine are increasing biomedicine offered hybrid fields. The oncoming generations of nanoscale biomedical/pharmaceutical products will have object specificity, carry multiple drugs, and potentially release the payloads at desired unreliable time periods. Nanotechnology is also opening up new opportunities in implantable delivery systems, which are often preferable to the use of injectable drugs, for the reason that the latter frequently show first order kinetics that may ground toxicity and decreased drug ability. Bioadhesive polymers have broadly been used in transmucosal drug delivery systems. These materials can be combined into pharmaceutical formulations, drug absorption by mucosal cells can be increased or the drug can be released at the position for an expanded duration of time. Over the past few years, nano particle ceramics have been broadly handled in a wide spectrum of biomedical requests, and drug delivery is one of the wildest developing and increasing areas for nanoceramics, drawing growing consideration. Certainly, researchers are recognizing that the amazing characteristics of nano particle ceramics exhibit excellent platforms for drug transportation and controlled release compared with polymeric platforms. This review defines various nano particle ceramics and bio/mucoadhesive polymers used in drug delivery. The presented data displays that these systems can be used excellently for continued release applications. They assure the basic demands of biocompatibility, drug loading and tolerated release sketches spreading to several weeks, and are proper materials for present implant technologies.

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تاریخ انتشار 2013